Saint-Gobain Life Sciences Introduces Highly Efficient Cell Culture Bags for T Cell Expansion

Gaithersburg, Md., United States: 

Saint-Gobain Life Sciences, an industry leader in material science-based solutions for cell and gene therapy manufacturing, today launched a new cell culture bag designed specifically for T cell derived therapies.

T cell based therapies are revolutionizing the approach to treating cancer. Harnessing the patient’s own immune system by isolating their T cells and engineering them to elicit an immune response is emerging as a preferred manufacturing practice. As the industry continues the advancement of these therapies, process efficiency becomes paramount to the success of delivering affordable therapies to patients.

Building upon the VueLife^® family of fluorinated ethylene propylene (FEP) based cell culture bags, VueLife^® “HP” (high permeability) incorporates an innovative, patented laminate film layer that allows increased CO₂ and O₂ exchange versus other monolayer bag designs, yet maintains the scalability and process flexibility offered by a closed bag system. The increased permeability associated with the “HP” laminate layer was specifically designed for culturing cells requiring higher rates of respiration, such as T cells.

“The development of this product was in direct response to the market need for a cost effective culture vessel that provides efficient cell expansion in a scalable, closed system,” said Benjamin Le Quere, General Manager for the Saint-Gobain Life Sciences Bioprocess Solutions business unit. “VueLife^® “HP” is an exciting result of the marrying of our expertise in material science with our knowledge in cell culture.”

The entire family of VueLife^® cell culture bags utilize a common FEP fluid-contact layer. FEP creates an ideal environment for cell growth due to its gas permeability and liquid impermeability, while being biologically and chemically inert.

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